The interaction of endorepellin and neurexin triggers neuroepithelial autophagy and maintains neural tube development Neural tube defects (NTDs) rank as the second most prevalent congenital malformation in humans, impacting the central nervous system development in approximately 1 in every 1,000 live births. Over 300 genes, including the HSPG2 gene, are implicated in NTDs in mice.
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