Second Phase 3 clinical trial again shows dupilumab lessens disease in COPD patients with type 2 inflammation Chronic obstructive pulmonary disease patients with type 2 inflammation may soon gain access to a new drug -- dupilumab -- that showed rapid and sustained improvements in patients in a pivotal Phase 3 clinical trial, researchers report. This monoclonal antibody is the first biologic shown to improve clinical outcomes in COPD.
https://www.sciencedaily.com/r....eleases/2024/05/2405

Discovery into how chronic lung conditions affect children's immune system Researchers have made a breakthrough into how two chronic respiratory diseases in childhood affect the immune system, paving the way for better treatments.
https://www.sciencedaily.com/r....eleases/2024/04/2404

How gum disease aggravates chronic obstructive pulmonary disease A new study shows how periodontitis, an oral disease, activates immune cells associated with aggravated progression of COPD.
https://www.sciencedaily.com/r....eleases/2024/01/2401

Advancing the generation of in-vivo chimeric lungs in mice using rat-derived stem cells Creating a functional lung using interspecies chimeric animals is an attractive albeit challenging option for lung transplantation, requiring more research on the viable conditions needed for organ generation. A new study uses reverse-blastocyst complementation and tetraploid-based organ complementation methods to first determine these conditions in lung-deficient mice and then to generate rat-derived lungs in these mice. It provides useful insights on the intrinsic species-specific barriers and factors associated with lung development in interspecies chimeric animals.
https://www.sciencedaily.com/r....eleases/2024/01/2401

Healthy omega-3 fats may slow deadly pulmonary fibrosis Higher levels of omega-3, the healthy fat found in fish and nuts, were associated with better lung function and longer transplant-free survival.
https://www.sciencedaily.com/r....eleases/2024/01/2401