Mild Cognitive Impairment and Dementia in Essential Tremor Cohort Congratulations to Dr. Michael Okun on the publication of “Mild Cognitive Impairment and Dementia in Essential Tremor Cohort,” which appears in the New England Journal of Medicine Journal Watch. Cognitive impairment has been shown to occur in many essential tremor (ET) cohorts. What has been lacking is a better understanding of conversion to mild cognitive…
https://neurology.ufl.edu/2025..../01/14/mild-cognitiv

Brain-derived tau oligomer polymorphs: distinct aggregations, stability profiles, and biological activities https://www.nature.com/articles/s42003-025-07499-w

Deficits in reaching movements under visual interference as a novel diagnostic marker for mild cognitive impairment https://www.nature.com/articles/s41598-025-85785-7

Effectiveness, safety, and impact on multiple sclerosis course of anti-CGRP monoclonal antibodies Migraine affects up to 40 % of people with multiple sclerosis (PwMS). This study aimed to evaluate the effectiveness and safety of the combination of antibodies (mAbs) against CGRP (anti-CGRP mAbs) with disease-modifying treatments (DMTs) for MS (mAb and non-mAbs) and their impact on MS disease course.
https://www.jns-journal.com/ar....ticle/S0022-510X(25)

Diagnostic clues in herpes encephalitis following radiation therapy Herpes encephalitis is known to affect patients undergoing brain radiotherapy, but early diagnosis and treatment, the foremost determinants of disease outcome, remain challenging in this patient population. This can be due to attribution of symptoms to the brain tumor and radiation side effects, as well as patients' atypical clinical presentation. Here we sought to highlight pearls and pitfalls in the clinical course and diagnostic workup which may facilitate timely diagnosis and improve disease outcome.
https://www.jns-journal.com/ar....ticle/S0022-510X(25)