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Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord.
https://medicalxpress.com/news..../2024-11-scientists-


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How cells recycle damaged mitochondria in middle age may be critical for brain health Mitochondria play an essential role in maintaining cellular health. When damaged, they are removed through a recycling process called mitophagy, which is crucial for the function of long-lived cells, especially in the brain. Impaired mitophagy has been strongly associated with neurodegenerative disorders like Alzheimer's and Parkinson's disease, making it a critical focus for drug discovery and therapeutic innovation.
https://medicalxpress.com/news..../2024-11-cells-recyc


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Distinct neural circuits mediate anti-anxiety and hallucination-like effects of psychedelics, research reveals New research suggests that it could be possible to separate treatment from hallucinations when developing new drugs based on psychedelics. The anti-anxiety and hallucination-inducing qualities of psychedelic drugs work through different neural circuits, according to research using a mouse model. The work is published in Science.
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Q&A: Generating data from neurons to teach AI the rules of the brain The 2024 Nobel Prizes in physics and chemistry were seen as a sweep for artificial intelligence (AI) tools which, at their conception, were inspired by neuroscience. By imitating the behavior of human brain cells, machine-learning algorithms are accelerating our understanding of basic biology, with technologies such as Google DeepMind's AlphaFold 3 making it possible to predict the structure of proteins or how they might interact with potential drugs.
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'It's my brain's fault': Why teenagers often make less than optimal decisions Adults exhibit a general tendency to make better decisions than adolescents, and this improvement drives an increase in specific and more sophisticated choice behaviors, according to a study published November 14 in PLOS Biology by Vanessa Scholz and Lorenz Deserno from the University of Würzburg, Germany, and colleagues.
https://medicalxpress.com/news..../2024-11-brain-fault


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