The common variable immunodeficiency IgM repertoire narrowly recognizes erythrocyte and platelet glycans Autoantibody-mediated cytopenias (AICs) regularly occur in profoundly IgG-deficient common variable immunodeficiency (CVID) patients. The isotypes, antigenic targets, and origin(s) of their disease-causing autoantibodies are unclear.
https://www.jacionline.org/art....icle/S0091-6749(24)0