Immune Cell Differences Must Be Considered in Epigenetic Age Epigenetic age is most commonly measured via blood sample, assessing the epigenetic markers of immune cells in that sample. Unfortunately the present mainstream epigenetic clocks will provide different ages for different immune cell populations. This leads to meaningful variation in assessments of the same individual, because different cell populations might be present in somewhat different proportions in each blood sample. We might also question which of the cell populations provide the most useful epigenetic age when it comes to responsiveness to interventions that might slow or reverse aspects of aging. This is a well known problem at this point in the continued development of epigenetic clocks, but there is as yet little consensus on what to do about it. Aging is a significant risk factor […]
https://www.fightaging.org/arc....hives/2024/05/immune