Scientists find a hidden weak spot that may trigger Alzheimer’s Scientists have found that a mutation tied to Alzheimer’s disrupts the production and quality of exosomes—tiny cell-made communication packets. Cells with the defective SORLA protein generate fewer exosomes and ones far less able to support nearby brain cells. This weakness may be a key driver of Alzheimer’s development. The research points to new treatment strategies that enhance or restore exosome function.
https://www.sciencedaily.com/r....eleases/2025/11/2511

Study finds untreated sleep apnea doubles Parkinson’s risk A massive veteran study found a strong connection between untreated sleep apnea and a higher chance of Parkinson’s. CPAP users had much lower odds of developing the condition. Researchers believe that repeated dips in oxygen during sleep may strain neurons over time. The results suggest that better sleep might help protect the brain.
https://www.sciencedaily.com/r....eleases/2025/11/2511

A common nutrient deficiency may be silently harming young brains Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment. The group showed higher inflammation, signs of liver strain and elevated neurofilament light chain, a marker of neuron injury. Low choline levels appeared closely tied to these changes. The results hint that early metabolic disruptions may quietly influence the brain long before symptoms emerge.
https://www.sciencedaily.com/r....eleases/2025/11/2511

Your body may already have a molecule that helps fight Alzheimer’s Spermine, a small but powerful molecule in the body, helps neutralize harmful protein accumulations linked to Alzheimer’s and Parkinson’s. It encourages these misfolded proteins to gather into manageable clumps that cells can more efficiently dispose of through autophagy. Experiments in nematodes show that spermine also enhances longevity and cellular energy production. These insights open the door to targeted therapies powered by polyamines and advanced AI-driven molecular design.
https://www.sciencedaily.com/r....eleases/2025/11/2511

Repeated head impacts may quietly break the brain’s cleanup system Researchers found that repeated head impacts can disrupt a key system that helps the brain wash away waste. In professional fighters, this system initially seems to work harder after trauma, then declines over time. MRI scans revealed that these changes may show up years before symptoms do. The work could help identify at-risk athletes earlier in their careers.
https://www.sciencedaily.com/r....eleases/2025/11/2511