How a hidden brain circuit fuels fibromyalgia, migraines, and PTSD What if your brain is the reason some pain feels unbearable? Scientists at the Salk Institute have discovered a hidden brain circuit that gives pain its emotional punch—essentially transforming ordinary discomfort into lasting misery. This breakthrough sheds light on why some people suffer more intensely than others from conditions like fibromyalgia, migraines, and PTSD. By identifying the exact group of neurons that link physical pain to emotional suffering, the researchers may have found a new target for treating chronic pain—without relying on addictive medications.
https://www.sciencedaily.com/r....eleases/2025/07/2507

Your Brain’s Hidden Defenses Against Alzheimer’s Scientists at UCSF combined advanced brain-network modeling, genetics, and imaging to reveal how tau protein travels through neural highways and how certain genes either accelerate its toxic journey or shield brain regions from damage. Their extended Network Diffusion Model pinpoints four gene categories that govern vulnerability or resilience, reshaping our view of Alzheimer’s progression and spotlighting fresh therapeutic targets.
https://www.sciencedaily.com/r....eleases/2025/07/2507

Alzheimer’s doesn’t strike at random: These 4 early-warning patterns tell the story UCLA scientists mined millions of electronic health records and uncovered four distinct “roadways” that funnel people toward Alzheimer’s—ranging from mental-health struggles to vascular troubles. Following these breadcrumb trails proved far better at predicting who will develop dementia than single risk factors. The findings hint that spotting—and halting—specific sequences early could rewrite how we prevent the disease.
https://www.sciencedaily.com/r....eleases/2025/07/2507

Scientists reverse Parkinson’s symptoms in mice — Could humans be next? Scientists at the University of Sydney have uncovered a malfunctioning version of the SOD1 protein that clumps inside brain cells and fuels Parkinson’s disease. In mouse models, restoring the protein’s function with a targeted copper supplement dramatically rescued movement, hinting at a future therapy that could slow or halt the disease in people.
https://www.sciencedaily.com/r....eleases/2025/07/2507

Cough medicine turned brain protector? Ambroxol may slow Parkinson’s dementia Ambroxol, long used for coughs in Europe, stabilized symptoms and brain-damage markers in Parkinson’s dementia patients over 12 months, whereas placebo patients worsened. Those with high-risk genes even saw cognitive gains, hinting at real disease-modifying power.
https://www.sciencedaily.com/r....eleases/2025/07/2507