Proximal native vessel disease progression : Is it good or bad following CABG ? No doctor will want any disease to progress in their patients. But, coronary revascularization is an enigma. Cardiologists take every step to regress the atherosclerotic process and be meticulous in maintaining antegrade flow across the left main and proximal LAD or LCX. They double up their caution after PCI in left main or proximal segments. […] https://drsvenkatesan.com/2025..../05/15/proximal-nati
Difference between central and peripheral adrenergic alpha receptors Understanding sympathetic nervous had never been easy. (It doesn’t in any way mean, we have mastered para-sympathetic !). As physicians and cardiologists, we are expected to know the updated adrenergic, dopaminergic, imidazoline receptors etc. We need to know at-least an overview of its current nomenclature, area of distribution, benefits of blocking and stimulating them. Unfortunately, […] https://drsvenkatesan.com/2025..../05/13/difference-be
Why DEBs are eluting Paclitaxel, while DES are eluting Sirolimus ? A brief review Paclitaxel: Is a highly lipophilic, and rapidly absorbed by vessel walls and retained for days to weeks, making it ideal for DEBs, which deliver the drug during brief balloon inflation (30–60 seconds). Its cytotoxic action, disrupting microtubules and arresting cells in the M-phase, effectively inhibits neointimal hyperplasia without requiring prolonged drug release. […] https://drsvenkatesan.com/2025..../05/13/why-debs-are-