A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice The development of peanut allergy is due to a combination of genetic and environmental factors, although specific genes have proven difficult to identify. Previously, we reported that peanut-sensitized CC027/GeniUnc (CC027) mice develop anaphylaxis upon oral challenge to peanut, unlike C3H/HeJ (C3H) mice.
https://www.jacionline.org/art....icle/S0091-6749(24)0