Modified inhibitors show promise against coronaviruses by targeting essential Mac1 protein domain
A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and MERS-CoV.
https://phys.org/news/2025-07-....inhibitors-coronavir
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