Single enzyme failure found to drive neuron loss in dementia Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis. The study provides the first molecular evidence that ferroptosis can drive neurodegeneration in the human brain. These findings open up new avenues for developing future therapies—particularly for severe early-onset childhood dementia.
https://medicalxpress.com/news..../2025-12-enzyme-fail