L-plastin associated syndrome of immune deficiency and haematological cytopenia (PASIC) LCP1 encodes L-plastin, an actin-bundling protein primarily expressed in hematopoietic cells. In mouse and fish models, LCP1 deficiency has been shown to result in hematological and immune defects.
https://www.jacionline.org/art....icle/S0091-6749(24)0

The nasal basal cell population shifts towards a diseased phenotype with impaired barrier formation capacity in allergic rhinitis Capsule summaryNasal basal cells are characterized by a diseased phenotype in allergic rhinitis and in vitro assays demonstrated that this is correlated with impaired barrier formation capacity, highlighting them as an interesting potential therapeutic target.
https://www.jacionline.org/art....icle/S0091-6749(24)0

IL-4Rα signaling promotes barrier-altering oncostatin M and IL-6 production in aspirin-exacerbated respiratory disease This study demonstrates overproduction of oncostatin M and IL-6 in nasal fluid in aspirin-exacerbated respiratory disease (AERD) and suggests that dupilumab-induced decrease of both oncostatin M and IL-6 contributes to its therapeutic efficacy in AERD.
https://www.jacionline.org/art....icle/S0091-6749(24)0

ALOX15+ M2 macrophages contribute to epithelial remodeling in eosinophilic chronic rhinosinusitis with nasal polyps https://www.jacionline.org/art....icle/S0091-6749(24)0

Ozempic: the popular weight-loss drug's association with cancer Ozempic is well-known for its popularity in mainstream media as a weight loss drug. However, it was (and still is) originally indicated to treat diabetes m
https://www.labroots.com/trend....ing/immunology/27009